Glabridin Solution
Glabridin is a flavonoid from Glycyrrhiza glabra roots. As a unique Chinese plant resource, it directly inhibits tyrosinase activity, blocking melanin synthesis — a scientifically proven, safe, and effective natural brightening ingredient. Its tyrosinase inhibition is 80× Vitamin C and 140× Niacinamide, earning it the title Brightening Gold.
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140 X
Tyrosinase inhibition is 140× of Niacinamide
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961 X
961× of α-arbutin
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80 X
80× of Vitamin C
Blue Bag Exclusive Upgrade
Application Field
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CosmeticGlabridin has become a star ingredient in high-end brightening skincare products due to its potent brightening, anti-inflammatory, and antioxidant properties. Its benefits include:
Brightening and spot reduction: Reduces melanin synthesis by blocking tyrosinase activity;
Anti-photoaging and antioxidant:Neutralizes UV-induced ROS, reducing photodamage;
Anti-inflammatory and soothing:Blocks the NF-κB pathway, reducing the release of pro-inflammatory cytokines such as IL-6 and TNF-α, alleviating redness and acne-related inflammation in sensitive skin;
Anti-glycation:Inhibits the formation of AGEs, reducing dullness and roughness of the skin.
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Food and health productsLicorice flavonoids, such as glabridin, possess numerous antioxidant and anti-inflammatory properties and are widely used in functional foods and health supplements:
Antioxidant:Scavenges free radicals, activates Nrf2, and promotes the expression of antioxidant enzymes;
Anti-inflammatory:Blocks nuclear translocation of NF-κB, reducing the production of pro-inflammatory factors;
Lowers blood sugar and lipid levels:Activates AMP-dependent protein kinase (AMPK), promoting fatty acid oxidation and glucose uptake, and improving insulin resistance.
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MedicineGlabridin has been shown to have therapeutic effects in pharmacological studies of many diseases, including:
Acute respiratory distress syndrome (ARDS), cardiovascular diseases (CVDs), anti-cancer research (breast cancer), autoimmune diseases (anti-inflammatory), pain management, anti-atherosclerosis and neuroprotection.


